This article examines the differences in protection levels provided by old and new versions of the vaccine for whooping cough disease and their impact on children.
Effectiveness of the Pertussis Vaccine
Data involving approximately 40,500 children born in 1998 who received three doses during infancy showed that the first type (whole-cell) provides stronger protection before children reach 12 years of age compared to the newer acellular type or a combination of both.
Annual incidence rates between 1999 and 2008 were recorded as follows:
- 5.2 cases per 100,000 children among recipients of the older vaccine.
- 13.2 cases per 100,000 children among recipients of the newer type.
During an epidemic period that began in 2009 and peaked in 2011, infections rose to 113 cases per 100,000 children in the older vaccine group, while the newer type group recorded 373 cases per 100,000 children.
Reasons for Developing the Modern Vaccine
The newer type of vaccine was developed in 1997 due to concerns regarding certain side effects associated with the whole-cell version, which primarily included:
- Swelling at the injection site.
- Fever.
Current research is focused on creating a vaccine that provides lifelong immunity starting from the first dose without causing any side effects.
Whooping Cough in Children and Mixed Immunity
Studies have shown that relying on a combination of both whole-cell and acellular vaccines provides better immunity, particularly if the first dose the child received was the whole-cell type. This helps mitigate the risks associated with whooping cough disease.
FAQ
Which type of vaccine provides greater protection against the disease?
The older whole-cell type has proven more effective in reducing the likelihood of infection compared to the modern acellular type.
What are the side effects of the old whole-cell vaccine?
This type of vaccine may lead to fever and swelling in the area where the injection was administered.
Is there a way to increase immunity against the disease?
A combination of whole-cell and acellular vaccines provides better immunity, especially when the vaccination process begins with the whole-cell type.
When to Visit a Doctor?
You should consult a healthcare provider immediately if a child shows acute respiratory signs, severe and persistent coughing fits, or difficulty breathing.
Disclaimer: This content is for informational purposes only and does not substitute for professional medical advice.
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Illustration: AI-generated
approved by: Medica Health team